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P11.46 Discovery of a new HDAC6 inhibitor for the treatment of glioblastoma

BACKGROUND: Glioblastoma’s origin and development is not only associated to genetic alterations, but also to epigenetic changes. Indeed, an altered expression or activity of epigenetic enzymes such as histone deacetylases (HDAC) has been associated to cancer stem cell activity, which has been widely...

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Publicado en:Neuro Oncol
Autores principales: Auzmendi-Iriarte, J, Saenz-Antoñanzas, A, Andermatten, J, Elua-Pinin, A, Aldaba, E, Vara, Y, Matheu, A
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796111/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.192
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