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P11.46 Discovery of a new HDAC6 inhibitor for the treatment of glioblastoma

BACKGROUND: Glioblastoma’s origin and development is not only associated to genetic alterations, but also to epigenetic changes. Indeed, an altered expression or activity of epigenetic enzymes such as histone deacetylases (HDAC) has been associated to cancer stem cell activity, which has been widely...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Neuro Oncol
Prif Awduron: Auzmendi-Iriarte, J, Saenz-Antoñanzas, A, Andermatten, J, Elua-Pinin, A, Aldaba, E, Vara, Y, Matheu, A
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796111/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz126.192
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