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Characterization of a new small-molecule inhibitor of HDAC6 in glioblastoma
Histone deacetylase 6 (HDAC6) is an epigenetic modifier that is an attractive pharmacological target in cancer. In this work, we show that HDAC6 is elevated in glioblastoma, the most malignant and common brain tumor in adults, in which its high levels correlate with poor patient survival and is more...
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| Pubblicato in: | Cell Death Dis |
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| Autori principali: | , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7265429/ https://ncbi.nlm.nih.gov/pubmed/32488056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2586-x |
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