Effects of Aryl Hydrocarbon Receptor Deficiency on PCB-77-Induced Impairment of Glucose Homeostasis during Weight Loss in Male and Female Obese Mice

BACKGROUND: Lipophilic polychlorinated biphenyls (PCBs) accumulate with obesity, but during weight loss, liberated PCBs act as ligands of the aryl hydrocarbon receptor (AhR) to negatively influence health. Previous studies demonstrated that PCB-77 administration to obese male mice impaired glucose t...

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Publicado en:Environ Health Perspect
Autores principales: Jackson, Erin N., Thatcher, Sean E., Larian, Nika, English, Victoria, Soman, Sony, Morris, Andrew J., Weng, Jiaying, Stromberg, Arnold, Swanson, Hollie I., Pearson, Kevin, Cassis, Lisa A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Environmental Health Perspectives 2019
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794491/
https://ncbi.nlm.nih.gov/pubmed/31306034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP4133
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