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Pseudomonas aeruginosa-derived pyocyanin reduces adipocyte differentiation, body weight, and fat mass as mechanisms contributing to septic cachexia

Pseudomonas aeruginosa, a leading cause of sepsis, produces pyocyanin, a blue-pigmented virulence factor. Sepsis is associated with cachexia, but mechanisms are unknown and conventional nutrition approaches are not effective. Pyocyanin has affinity for the aryl hydrocarbon receptor (AhR), which is e...

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Bibliografische gegevens
Gepubliceerd in:Food Chem Toxicol
Hoofdauteurs: Larian, Nika, Ensor, Mark, Thatcher, Sean E., English, Victoria, Morris, Andrew J., Stromberg, Arnold, Cassis, Lisa A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6557674/
https://ncbi.nlm.nih.gov/pubmed/31078726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2019.05.012
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