Effects of Aryl Hydrocarbon Receptor Deficiency on PCB-77-Induced Impairment of Glucose Homeostasis during Weight Loss in Male and Female Obese Mice

BACKGROUND: Lipophilic polychlorinated biphenyls (PCBs) accumulate with obesity, but during weight loss, liberated PCBs act as ligands of the aryl hydrocarbon receptor (AhR) to negatively influence health. Previous studies demonstrated that PCB-77 administration to obese male mice impaired glucose t...

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Détails bibliographiques
Publié dans:Environ Health Perspect
Auteurs principaux: Jackson, Erin N., Thatcher, Sean E., Larian, Nika, English, Victoria, Soman, Sony, Morris, Andrew J., Weng, Jiaying, Stromberg, Arnold, Swanson, Hollie I., Pearson, Kevin, Cassis, Lisa A.
Format: Artigo
Langue:Inglês
Publié: Environmental Health Perspectives 2019
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794491/
https://ncbi.nlm.nih.gov/pubmed/31306034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/EHP4133
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