Coplanar Polychlorinated Biphenyls Impair Glucose Homeostasis in Lean C57BL/6 Mice and Mitigate Beneficial Effects of Weight Loss on Glucose Homeostasis in Obese Mice

Background: Previous studies demonstrated that coplanar polychlorinated biphenyls (PCBs) promote proinflammatory gene expression in adipocytes. PCBs are highly lipophilic and accumulate in adipose tissue, a site of insulin resistance in persons with type 2 diabetes. Objectives: We investigated the i...

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Hlavní autoři: Baker, Nicki A., Karounos, Michael, English, Victoria, Fang, Jun, Wei, Yinan, Stromberg, Arnold, Sunkara, Manjula, Morris, Andrew J., Swanson, Hollie I., Cassis, Lisa A.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Institute of Environmental Health Sciences 2012
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3553436/
https://ncbi.nlm.nih.gov/pubmed/23099484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1205421
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