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Regulated spindle orientation buffers tissue growth in the epidermis

Tissue homeostasis requires a balance between progenitor cell proliferation and loss. Mechanisms that maintain this robust balance are needed to avoid tissue loss or overgrowth. Here we demonstrate that regulation of spindle orientation/asymmetric cell divisions is one mechanism that is used to buff...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Morrow, Angel, Underwood, Julie, Seldin, Lindsey, Hinnant, Taylor, Lechler, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6794086/
https://ncbi.nlm.nih.gov/pubmed/31577227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.48482
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