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A transgenic toolkit for visualizing and perturbing microtubules reveals unexpected functions in the epidermis

The physiological functions of microtubules (MTs) are poorly understood in many differentiated cell types. We developed a genetic toolkit to study MT dynamics and function in diverse cells. Using TRE-EB1-GFP mice, we found that MT dynamics are strongly suppressed in differentiated keratinocytes in t...

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Bibliographic Details
Published in:eLife
Main Authors: Muroyama, Andrew, Lechler, Terry
Format: Artigo
Language:Inglês
Published: eLife Sciences Publications, Ltd 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5605193/
https://ncbi.nlm.nih.gov/pubmed/28869035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.29834
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