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NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures

Mitotic spindle orientation is used to generate cell fate diversity and drive proper tissue morphogenesis. A complex of NuMA and dynein/dynactin is required for robust spindle orientation in a number of cell types. Previous research proposed that cortical dynein/dynactin was sufficient to generate f...

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Publicat a:eLife
Autors principals: Seldin, Lindsey, Muroyama, Andrew, Lechler, Terry
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4758947/
https://ncbi.nlm.nih.gov/pubmed/26765568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.12504
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