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Epithelial geometry regulates spindle orientation and progenitor fate during formation of the mammalian epidermis

The control of cell fate through oriented cell division is imperative for proper organ development. Basal epidermal progenitor cells divide parallel or perpendicular to the basement membrane to self-renew or produce differentiated stratified layers, but the mechanisms regulating the choice between d...

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Detalles Bibliográficos
Publicado en:eLife
Autores principales: Box, Kimberly, Joyce, Bradley W, Devenport, Danelle
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6592681/
https://ncbi.nlm.nih.gov/pubmed/31187731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47102
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