p53 Expression Induces Apoptosis in Hippocampal Pyramidal Neuron Cultures

The tumor suppressor gene p53 has been implicated in the induction of apoptosis in dividing cells. We now show that overexpression of p53 using an adenoviral vector in cultured rat hippocampal pyramidal neurons causes widespread neuronal death with features typical of apoptosis. p53 overexpression d...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Jordán, Joaquín, Galindo, María F., Prehn, Jochen H. M., Weichselbaum, Ralph R., Beckett, Michael, Ghadge, Ghanashyam D., Roos, Raymond P., Leiden, Jeffrey M., Miller, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 1997
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793734/
https://ncbi.nlm.nih.gov/pubmed/9006981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-04-01397.1997
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi