Estrogen Alters Spine Number and Morphology in Prefrontal Cortex of Aged Female Rhesus Monkeys

Long-term cyclic treatment with 17β-estradiol reverses age-related impairment in ovariectomized rhesus monkeys on a test of cognitive function mediated by the prefrontal cortex (PFC). Here, we examined potential neurobiological substrates of this effect using intracellular loading and morphometric a...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Hao, Jiandong, Rapp, Peter R., Leffler, Abba E., Leffler, Shoshana R., Janssen, William G. M., Lou, Wendy, McKay, Heather, Roberts, Jeffrey A., Wearne, Susan L., Hof, Patrick R., Morrison, John H.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793646/
https://ncbi.nlm.nih.gov/pubmed/16510735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3440-05.2006
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