Motoneuron Apoptosis Is Blocked by CEP-1347 (KT 7515), a Novel Inhibitor of the JNK Signaling Pathway

Neurons undergoing apoptosis can be rescued by trophic factors that simultaneously increase the activity of extracellular signal-regulated kinase (ERK) and decrease c-Jun N-terminal kinase (JNK) and p38. We identified a molecule, CEP-1347 (KT7515), that rescues motoneurons undergoing apoptosis and i...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Maroney, Anna C., Glicksman, Marcie A., Basma, Alie N., Walton, Kevin M., Knight, Ernest, Murphy, Carol A., Bartlett, Becky A., Finn, James P., Angeles, Thelma, Matsuda, Yuzuru, Neff, Nicola T., Dionne, Craig A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793399/
https://ncbi.nlm.nih.gov/pubmed/9412490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-01-00104.1998
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