Degeneration In Vivo of Rat Hippocampal Neurons by Wild-Type Alzheimer Amyloid Precursor Protein Overexpressed by Adenovirus-Mediated Gene Transfer

In an attempt to elucidate the pathological implications of intracellular accumulation of the amyloid precursor protein (APP) in postmitotic neurons in vivo, we transferred APP695 cDNA into rat hippocampal neurons by using a replication-defective adenovirus vector. We first improved the efficiency o...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Nishimura, Isao, Uetsuki, Taichi, Dani, Sergio U., Ohsawa, Yoshiyuki, Saito, Izumu, Okamura, Hitoshi, Uchiyama, Yasuo, Yoshikawa, Kazuaki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 1998
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6793123/
https://ncbi.nlm.nih.gov/pubmed/9502800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-07-02387.1998
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