Disruption of the Paternal Necdin Gene Diminishes TrkA Signaling for Sensory Neuron Survival

Necdin is a multifunctional signaling protein that stabilizes terminal differentiation of postmitotic neurons. The human necdin gene in chromosome 15q11-q12 is maternally imprinted, paternally transcribed, and not expressed in Prader-Willi syndrome, a human genomic imprinting-associated neurodevelop...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Kuwako, Ken-ichiro, Hosokawa, Akari, Nishimura, Isao, Uetsuki, Taichi, Yamada, Masashi, Nada, Shigeyuki, Okada, Masato, Yoshikawa, Kazuaki
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6724840/
https://ncbi.nlm.nih.gov/pubmed/16049186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2083-05.2005
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