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A Point Mutation (D79N) of the α2A Adrenergic Receptor Abolishes the Antiepileptogenic Action of Endogenous Norepinephrine

Norepinephrine serves as a neurotransmitter for a population of neurons the cell bodies of which reside in a brainstem nucleus and the axons of which project widely to discrete subsets of forebrain neurons. Norepinephrine powerfully inhibits epileptogenesis in the kindling model. Pharmacological met...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Janumpalli, Sridevi, Butler, Linda S., MacMillan, Leigh B., Limbird, Lee E., McNamara, James O.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 1998
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792932/
https://ncbi.nlm.nih.gov/pubmed/9482787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-06-02004.1998
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