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The α(2a) Adrenergic Receptor Subtype Mediates Spinal Analgesia Evoked by α(2) Agonists and Is Necessary for Spinal Adrenergic–Opioid Synergy

Agonists acting at α(2) adrenergic and opioid receptors have analgesic properties and act synergistically when co-administered in the spinal cord; this synergy may also contribute to the potency and efficacy of spinally administered morphine. The lack of subtype-selective pharmacological agents has...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Stone, Laura S., MacMillan, Leigh B., Kitto, Kelley F., Limbird, Lee E., Wilcox, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6573259/
https://ncbi.nlm.nih.gov/pubmed/9278550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.17-18-07157.1997
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