Protein Kinase C Mediates the Synergistic Interaction Between Agonists Acting at α(2)-Adrenergic and Delta-Opioid Receptors in Spinal Cord

Coactivation of spinal α(2)-adrenergic receptors (ARs) and opioid receptors produces antinociceptive synergy. Antinociceptive synergy between intrathecally administered α(2)AR and opioid agonists is well documented, but the mechanism underlying this synergy remains unclear. The delta-opioid receptor...

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Detalhes bibliográficos
Main Authors: Overland, Aaron C., Kitto, Kelley F., Chabot-Doré, Anne-Julie, Rothwell, Patrick E., Fairbanks, Carolyn A., Stone, Laura S., Wilcox, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819727/
https://ncbi.nlm.nih.gov/pubmed/19846714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1907-09.2009
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