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Role of the Jun Kinase Pathway in the Regulation of c-Jun Expression and Apoptosis in Sympathetic Neurons

When deprived of nerve growth factor (NGF), developing sympathetic neurons die by apoptosis. This death is associated with an increase in the level of c-Jun protein and is blocked by expression of a c-Jun dominant negative mutant. Here we have investigated whether NGF withdrawal activates Jun kinase...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Eilers, Andreas, Whitfield, Jonathan, Babij, Carol, Rubin, Lee L., Ham, Jonathan
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792616/
https://ncbi.nlm.nih.gov/pubmed/9464996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-05-01713.1998
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