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Role of the Jun Kinase Pathway in the Regulation of c-Jun Expression and Apoptosis in Sympathetic Neurons

When deprived of nerve growth factor (NGF), developing sympathetic neurons die by apoptosis. This death is associated with an increase in the level of c-Jun protein and is blocked by expression of a c-Jun dominant negative mutant. Here we have investigated whether NGF withdrawal activates Jun kinase...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Eilers, Andreas, Whitfield, Jonathan, Babij, Carol, Rubin, Lee L., Ham, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792616/
https://ncbi.nlm.nih.gov/pubmed/9464996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-05-01713.1998
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