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The proapoptotic dp5 gene is a direct target of the MLK-JNK-c-Jun pathway in sympathetic neurons

The death of sympathetic neurons after nerve growth factor (NGF) withdrawal requires de novo gene expression. Dp5 was one of the first NGF withdrawal-induced genes to be identified and it encodes a proapoptotic BH3-only member of the Bcl-2 family. To study how dp5 transcription is regulated by NGF w...

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Detalhes bibliográficos
Main Authors: Towers, Emily, Gilley, Jonathan, Randall, Rebecca, Hughes, Rosie, Kristiansen, Mark, Ham, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685101/
https://ncbi.nlm.nih.gov/pubmed/19304750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp175
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