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Phosphorylation of c-Jun Is Necessary for Apoptosis Induced by Survival Signal Withdrawal in Cerebellar Granule Neurons

Cerebellar granule neurons die by apoptosis when deprived of survival signals. This death can be blocked by inhibitors of transcription or protein synthesis, suggesting that new gene expression is required. Here we show that c-jun mRNA and protein levels increase rapidly after survival signal withdr...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Watson, Andrea, Eilers, Andreas, Lallemand, Dominique, Kyriakis, John, Rubin, Lee L., Ham, Jonathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792526/
https://ncbi.nlm.nih.gov/pubmed/9425017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.18-02-00751.1998
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