Multisite phosphorylation of c-Jun at threonine 91/93/95 triggers the onset of c-Jun pro-apoptotic activity in cerebellar granule neurons

Cerebellar granule cell (CGC) apoptosis by trophic/potassium (TK) deprivation is a model of election to study the interplay of pro-apoptotic and pro-survival signaling pathways in neuronal cell death. In this model, the c-Jun N-terminal kinase (JNK) induces pro-apoptotic genes through the c-Jun/acti...

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Detalhes bibliográficos
Main Authors: Reddy, C E, Albanito, L, De Marco, P, Aiello, D, Maggiolini, M, Napoli, A, Musti, A M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3824690/
https://ncbi.nlm.nih.gov/pubmed/24113186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.381
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