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Advanced Glycation End Products (AGEs) Induce Apoptosis of Fibroblasts by Activation of NLRP3 Inflammasome via Reactive Oxygen Species (ROS) Signaling Pathway

BACKGROUND: Type 2 diabetes impairs the healing process and induces apoptosis of fibroblasts, which are thought to be involved in this process. We investigated the possible mechanisms involved in AGEs-induced apoptosis of human dermal fibroblasts. MATERIAL/METHODS: We examined the expression of apop...

詳細記述

保存先:
書誌詳細
出版年:Med Sci Monit
主要な著者: Dai, Jiezhi, Chen, Hua, Chai, Yimin
フォーマット: Artigo
言語:Inglês
出版事項: International Scientific Literature, Inc. 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6792499/
https://ncbi.nlm.nih.gov/pubmed/31587010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.915806
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