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p53 defies convention again: a p53 mutant that has lost tumor suppression but still can kill
Loss of tumor suppression by the p53 protein involves altered or abrogated transcriptional activity resulting in a failure to mediate wild‐type cellular responses including cell cycle arrest, senescence, and apoptosis. Timofeev et al (2019) make the fascinating finding that a novel p53 cooperativity...
Kaydedildi:
| Yayımlandı: | EMBO J |
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| Yazar: | |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
John Wiley and Sons Inc.
2019
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6792014/ https://ncbi.nlm.nih.gov/pubmed/31553097 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2019103322 |
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