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Cyclin F‐dependent degradation of E2F7 is critical for DNA repair and G2‐phase progression
E2F7 and E2F8 act as tumor suppressors via transcriptional repression of genes involved in S‐phase entry and progression. Previously, we demonstrated that these atypical E2Fs are degraded by APC/C(C) (dh1) during G1 phase of the cell cycle. However, the mechanism driving the downregulation of atypic...
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| Publicado no: | EMBO J |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6792010/ https://ncbi.nlm.nih.gov/pubmed/31475738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2018101430 |
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