Feedback regulation between atypical E2Fs and APC/C(C) (dh1) coordinates cell cycle progression

E2F transcription factors control the oscillating expression pattern of multiple target genes during the cell cycle. Activator E2Fs, E2F1–3, induce an upswing of E2F targets, which is essential for the G1‐to‐S phase transition, whereas atypical E2Fs, E2F7 and E2F8, mediate a downswing of the same ta...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Boekhout, Michiel, Yuan, Ruixue, Wondergem, Annelotte P, Segeren, Hendrika A, van Liere, Elsbeth A, Awol, Nesibu, Jansen, Imke, Wolthuis, Rob MF, de Bruin, Alain, Westendorp, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772983/
https://ncbi.nlm.nih.gov/pubmed/26882548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540984
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