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Feedback regulation between atypical E2Fs and APC/C(C) (dh1) coordinates cell cycle progression

E2F transcription factors control the oscillating expression pattern of multiple target genes during the cell cycle. Activator E2Fs, E2F1–3, induce an upswing of E2F targets, which is essential for the G1‐to‐S phase transition, whereas atypical E2Fs, E2F7 and E2F8, mediate a downswing of the same ta...

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Bibliografiske detaljer
Udgivet i:EMBO Rep
Main Authors: Boekhout, Michiel, Yuan, Ruixue, Wondergem, Annelotte P, Segeren, Hendrika A, van Liere, Elsbeth A, Awol, Nesibu, Jansen, Imke, Wolthuis, Rob MF, de Bruin, Alain, Westendorp, Bart
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4772983/
https://ncbi.nlm.nih.gov/pubmed/26882548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201540984
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