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APC/C(C)(dh1) controls CtIP stability during the cell cycle and in response to DNA damage

Human cells have evolved elaborate mechanisms for responding to DNA damage to maintain genome stability and prevent carcinogenesis. For instance, the cell cycle can be arrested at different stages to allow time for DNA repair. The APC/C(C)(dh1) ubiquitin ligase mainly regulates mitotic exit but is a...

詳細記述

保存先:
書誌詳細
出版年:EMBO J
主要な著者: Lafranchi, Lorenzo, de Boer, Harmen R, de Vries, Elisabeth GE, Ong, Shao-En, Sartori, Alessandro A, van Vugt, Marcel ATM
フォーマット: Artigo
言語:Inglês
出版事項: Blackwell Publishing Ltd 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4282561/
https://ncbi.nlm.nih.gov/pubmed/25349192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489017
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