Atypical E2Fs either Counteract or Cooperate with RB during Tumorigenesis Depending on Tissue Context

SIMPLE SUMMARY: In virtually all human malignancies, the CDK-RB-E2F pathway is dysregulated resulting in the activation of the E2F transcriptional network. Rb and atypical E2Fs are the most important negative regulators of E2F-dependent transcription during tumorigenesis. However, it is unknown whet...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cancers (Basel)
Main Authors: Moreno, Eva, Pandit, Shusil K., Toussaint, Mathilda J. M., Bongiovanni, Laura, Harkema, Liesbeth, van Essen, Saskia C., van Liere, Elsbeth A., Westendorp, Bart, de Bruin, Alain
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2021
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8122802/
https://ncbi.nlm.nih.gov/pubmed/33922435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers13092033
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker