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Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding

BACKGROUND: Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARH) control energy homeostasis by sensing hormonal and nutrient cues and activating secondary melanocortin sensing neurons. We identified the expression of a G protein-coupled receptor, Gpr17, in the ARH and...

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Bibliografski detalji
Izdano u:Nutr Diabetes
Glavni autori: Reilly, Austin M., Zhou, Shudi, Panigrahi, Sunil K., Yan, Shijun, Conley, Jason M., Sheets, Patrick L., Wardlaw, Sharon L., Ren, Hongxia
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791877/
https://ncbi.nlm.nih.gov/pubmed/31611548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-019-0096-7
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