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Pro-opiomelanocortin (POMC) modulates the thermogenic and physical activity responses to high fat feeding and markedly influences dietary fat preference
Complete POMC deficiency causes a human syndrome of hypoadrenalism, altered skin and hair pigmentation and severe hyperphagic obesity. Heterozygote carriers of nonsense mutations are strongly predisposed to obesity. Pomc(+/-) mice have normal body weight on a chow diet but increase food intake and b...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2204084/ https://ncbi.nlm.nih.gov/pubmed/17717049 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0797 |
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