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Pro-opiomelanocortin (POMC) modulates the thermogenic and physical activity responses to high fat feeding and markedly influences dietary fat preference

Complete POMC deficiency causes a human syndrome of hypoadrenalism, altered skin and hair pigmentation and severe hyperphagic obesity. Heterozygote carriers of nonsense mutations are strongly predisposed to obesity. Pomc(+/-) mice have normal body weight on a chow diet but increase food intake and b...

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Bibliografski detalji
Glavni autori: Tung, YC Loraine, Rimmington, Debra, O’Rahilly, Stephen, Coll, Anthony P
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2204084/
https://ncbi.nlm.nih.gov/pubmed/17717049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-0797
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