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Gpr17 deficiency in POMC neurons ameliorates the metabolic derangements caused by long-term high-fat diet feeding

BACKGROUND: Proopiomelanocortin (POMC) neurons in the arcuate nucleus of the hypothalamus (ARH) control energy homeostasis by sensing hormonal and nutrient cues and activating secondary melanocortin sensing neurons. We identified the expression of a G protein-coupled receptor, Gpr17, in the ARH and...

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Detalhes bibliográficos
Publicado no:Nutr Diabetes
Main Authors: Reilly, Austin M., Zhou, Shudi, Panigrahi, Sunil K., Yan, Shijun, Conley, Jason M., Sheets, Patrick L., Wardlaw, Sharon L., Ren, Hongxia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791877/
https://ncbi.nlm.nih.gov/pubmed/31611548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41387-019-0096-7
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