Telomerase activation in small intestinal neuroendocrine tumours is associated with aberrant TERT promoter methylation, but not hot-spot mutations

Telomere maintenance is a critical requirement for enabling replicative immortality and tumour development. Here, telomerase expression and activity, telomere length (TL) and potential regulatory factors that can underlie telomerase machinery alterations in small intestinal neuroendocrine tumours (S...

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Publicat a:Epigenetics
Autors principals: Fotouhi, Omid, Ghaderi, Mehran, Wang, Na, Zedenius, Jan, Kjellman, Magnus, Xu, Dawei, Juhlin, C. Christofer, Larsson, Catharina
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2019
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791720/
https://ncbi.nlm.nih.gov/pubmed/31322481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1634987
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