Global hypomethylation and promoter methylation in small intestinal neuroendocrine tumors: An in vivo and in vitro study

Aberrant DNA methylation is a feature of human cancer affecting gene expression and tumor phenotype. Here, we quantified promoter methylation of candidate genes and global methylation in 44 small intestinal-neuroendocrine tumors (SI-NETs) from 33 patients by pyrosequencing. Findings were compared wi...

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Библиографические подробности
Главные авторы: Fotouhi, Omid, Adel Fahmideh, Maral, Kjellman, Magnus, Sulaiman, Luqman, Höög, Anders, Zedenius, Jan, Hashemi, Jamileh, Larsson, Catharina
Формат: Artigo
Язык:Inglês
Опубликовано: Landes Bioscience 2014
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Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4143414/
https://ncbi.nlm.nih.gov/pubmed/24762809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.28936
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