Telomerase activation in small intestinal neuroendocrine tumours is associated with aberrant TERT promoter methylation, but not hot-spot mutations

Telomere maintenance is a critical requirement for enabling replicative immortality and tumour development. Here, telomerase expression and activity, telomere length (TL) and potential regulatory factors that can underlie telomerase machinery alterations in small intestinal neuroendocrine tumours (S...

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Detalhes bibliográficos
Publicado no:Epigenetics
Main Authors: Fotouhi, Omid, Ghaderi, Mehran, Wang, Na, Zedenius, Jan, Kjellman, Magnus, Xu, Dawei, Juhlin, C. Christofer, Larsson, Catharina
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791720/
https://ncbi.nlm.nih.gov/pubmed/31322481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15592294.2019.1634987
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