Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma

Medullary thyroid carcinomas (MTCs) exhibit telomerase activation in strong association with shorter patient survival. To understand the background of telomerase activation we quantified TERT copy numbers and TERT promoter methylation in 42 MTCs and normal thyroid references. Gain of TERT was demons...

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發表在:Oncotarget
Main Authors: Wang, Na, Kjellin, Hanna, Sofiadis, Anastasios, Fotouhi, Omid, Juhlin, C. Christofer, Bäckdahl, Martin, Zedenius, Jan, Xu, Dawei, Lehtiö, Janne, Larsson, Catharina
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008288/
https://ncbi.nlm.nih.gov/pubmed/26870890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7237
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