Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma

Medullary thyroid carcinomas (MTCs) exhibit telomerase activation in strong association with shorter patient survival. To understand the background of telomerase activation we quantified TERT copy numbers and TERT promoter methylation in 42 MTCs and normal thyroid references. Gain of TERT was demons...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Wang, Na, Kjellin, Hanna, Sofiadis, Anastasios, Fotouhi, Omid, Juhlin, C. Christofer, Bäckdahl, Martin, Zedenius, Jan, Xu, Dawei, Lehtiö, Janne, Larsson, Catharina
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008288/
https://ncbi.nlm.nih.gov/pubmed/26870890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7237
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