Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma

Medullary thyroid carcinomas (MTCs) exhibit telomerase activation in strong association with shorter patient survival. To understand the background of telomerase activation we quantified TERT copy numbers and TERT promoter methylation in 42 MTCs and normal thyroid references. Gain of TERT was demons...

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Udgivet i:Oncotarget
Main Authors: Wang, Na, Kjellin, Hanna, Sofiadis, Anastasios, Fotouhi, Omid, Juhlin, C. Christofer, Bäckdahl, Martin, Zedenius, Jan, Xu, Dawei, Lehtiö, Janne, Larsson, Catharina
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008288/
https://ncbi.nlm.nih.gov/pubmed/26870890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7237
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