Genetic and epigenetic background and protein expression profiles in relation to telomerase activation in medullary thyroid carcinoma

Medullary thyroid carcinomas (MTCs) exhibit telomerase activation in strong association with shorter patient survival. To understand the background of telomerase activation we quantified TERT copy numbers and TERT promoter methylation in 42 MTCs and normal thyroid references. Gain of TERT was demons...

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Bibliografiska uppgifter
I publikationen:Oncotarget
Huvudupphovsmän: Wang, Na, Kjellin, Hanna, Sofiadis, Anastasios, Fotouhi, Omid, Juhlin, C. Christofer, Bäckdahl, Martin, Zedenius, Jan, Xu, Dawei, Lehtiö, Janne, Larsson, Catharina
Materialtyp: Artigo
Språk:Inglês
Publicerad: Impact Journals LLC 2016
Ämnen:
Research Paper
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5008288/
https://ncbi.nlm.nih.gov/pubmed/26870890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7237
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