Apoptotic caspases inhibit abscopal responses to radiation and identify a new prognostic biomarker for breast cancer patients

Caspase 3 (CASP3) has a key role in the execution of apoptosis, and many cancer cells are believed to disable CASP3 as a mechanism of resistance to cytotoxic therapeutics. Alongside, CASP3 regulates stress-responsive immunomodulatory pathways, including secretion of type I interferon (IFN). Here, we...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Rodriguez-Ruiz, Maria Esperanza, Buqué, Aitziber, Hensler, Michal, Chen, Jonathan, Bloy, Norma, Petroni, Giulia, Sato, Ai, Yamazaki, Takahiro, Fucikova, Jitka, Galluzzi, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791460/
https://ncbi.nlm.nih.gov/pubmed/31646105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1655964
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