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Apoptotic caspases cut down the immunogenicity of radiation

Caspases are known for their ability to precipitate apoptosis. Our findings indicate that accelerating the terminal inactivation of cells dying in response to radiation therapy limit their immunogenicity as a consequence of reduced type I interferon secretion. Thus, caspase inhibitors stand out as p...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Buqué, Aitziber, Rodriguez-Ruiz, Maria Esperanza, Fucikova, Jitka, Galluzzi, Lorenzo
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791433/
https://ncbi.nlm.nih.gov/pubmed/31646103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1655364
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