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Prevention of breast cancer by RANKL/RANK blockade

Robust genetic evidence in mice and humans indicates that RANK signaling plays a major role in mammary carcinogenesis driven by BRCA1/BRCA2 mutations. These findings may inaugurate a new era of breast cancer prevention, changing the life of millions of women worldwide.

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Sonraí Bibleagrafaíochta
Foilsithe in:Cell Res
Main Authors: Galluzzi, Lorenzo, Buqué, Aitziber, Kroemer, Guido
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129887/
https://ncbi.nlm.nih.gov/pubmed/27325297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2016.79
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