The tumor suppressor FBXO31 preserves genomic integrity by regulating DNA replication and segregation through precise control of cyclin A levels

F-box protein 31 (FBXO31) is a reported putative tumor suppressor, and its inactivation due to loss of heterozygosity is associated with cancers of different origins. An emerging body of literature has documented FBXO31's role in preserving genome integrity following DNA damage and in the cell...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Dutta, Parul, Islam, Sehbanul, Choppara, Srinadh, Sengupta, Pallabi, Kumar, Anil, Kumar, Avinash, Wani, Mohan R., Chatterjee, Subhrangsu, Santra, Manas Kumar
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791333/
https://ncbi.nlm.nih.gov/pubmed/31413110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007055
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