The tumor suppressor FBXO31 preserves genomic integrity by regulating DNA replication and segregation through precise control of cyclin A levels

F-box protein 31 (FBXO31) is a reported putative tumor suppressor, and its inactivation due to loss of heterozygosity is associated with cancers of different origins. An emerging body of literature has documented FBXO31's role in preserving genome integrity following DNA damage and in the cell...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Dutta, Parul, Islam, Sehbanul, Choppara, Srinadh, Sengupta, Pallabi, Kumar, Anil, Kumar, Avinash, Wani, Mohan R., Chatterjee, Subhrangsu, Santra, Manas Kumar
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2019
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791333/
https://ncbi.nlm.nih.gov/pubmed/31413110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.007055
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