Genome-wide mapping of regions preferentially targeted by the human DNA-cytosine deaminase APOBEC3A using uracil-DNA pulldown and sequencing

Activation-induced deaminase (AID) and apolipoprotein B mRNA-editing enzyme catalytic subunit (APOBEC) enzymes convert cytosines to uracils, creating signature mutations that have been used to predict sites targeted by these enzymes. Mutation-based targeting maps are distorted by the error-prone or...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Sakhtemani, Ramin, Senevirathne, Vimukthi, Stewart, Jessica, Perera, Madusha L. W., Pique-Regi, Roger, Lawrence, Michael S., Bhagwat, Ashok S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Methods and Resources
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791317/
https://ncbi.nlm.nih.gov/pubmed/31431505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.008053
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