High Effectiveness in Actions of Carfilzomib on Delayed-Rectifier K(+) Current and on Spontaneous Action Potentials

Carfilzomib (CFZ, Kyprolis(®)) is widely recognized as an irreversible inhibitor of proteasome activity; however, its actions on ion currents in electrically excitable cells are largely unresolved. The possible actions of CFZ on ionic currents and membrane potential in pituitary GH(3), A7r5 vascular...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Front Pharmacol
Egile Nagusiak: So, Edmund Cheung, Liu, Ping-Yen, Lee, Chien-Ching, Wu, Sheng-Nan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Frontiers Media S.A. 2019
Gaiak:
Pharmacology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6791059/
https://ncbi.nlm.nih.gov/pubmed/31649537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01163
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