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High Effectiveness in Actions of Carfilzomib on Delayed-Rectifier K(+) Current and on Spontaneous Action Potentials
Carfilzomib (CFZ, Kyprolis(®)) is widely recognized as an irreversible inhibitor of proteasome activity; however, its actions on ion currents in electrically excitable cells are largely unresolved. The possible actions of CFZ on ionic currents and membrane potential in pituitary GH(3), A7r5 vascular...
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| Publicado no: | Front Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6791059/ https://ncbi.nlm.nih.gov/pubmed/31649537 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.01163 |
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