Industrial Trans Fatty Acids Stimulate SREBP2‐Mediated Cholesterogenesis and Promote Non‐Alcoholic Fatty Liver Disease

SCOPE: The mechanisms underlying the deleterious effects of trans fatty acids on plasma cholesterol and non‐alcoholic fatty liver disease (NAFLD) are unclear. Here, the aim is to investigate the molecular mechanisms of action of industrial trans fatty acids. METHODS AND RESULTS: Hepa1‐6 hepatoma cel...

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Dettagli Bibliografici
Pubblicato in:Mol Nutr Food Res
Autori principali: Oteng, Antwi‐Boasiako, Loregger, Anke, van Weeghel, Michel, Zelcer, Noam, Kersten, Sander
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790681/
https://ncbi.nlm.nih.gov/pubmed/31327168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201900385
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