Industrial Trans Fatty Acids Stimulate SREBP2‐Mediated Cholesterogenesis and Promote Non‐Alcoholic Fatty Liver Disease

SCOPE: The mechanisms underlying the deleterious effects of trans fatty acids on plasma cholesterol and non‐alcoholic fatty liver disease (NAFLD) are unclear. Here, the aim is to investigate the molecular mechanisms of action of industrial trans fatty acids. METHODS AND RESULTS: Hepa1‐6 hepatoma cel...

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Detalhes bibliográficos
Publicado no:Mol Nutr Food Res
Main Authors: Oteng, Antwi‐Boasiako, Loregger, Anke, van Weeghel, Michel, Zelcer, Noam, Kersten, Sander
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6790681/
https://ncbi.nlm.nih.gov/pubmed/31327168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mnfr.201900385
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