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Feeding Angptl4(−/−) mice trans fat promotes foam cell formation in mesenteric lymph nodes without leading to ascites
Angiopoietin-like 4 (ANGPTL4) regulates plasma triglyceride levels by inhibiting LPL. Inactivation of ANGPTL4 decreases plasma triglycerides and reduces the risk of coronary artery disease. Unfortunately, targeting ANGPTL4 for the therapeutic management of dyslipidemia and atherosclerosis is hampere...
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| Udgivet i: | J Lipid Res |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The American Society for Biochemistry and Molecular Biology
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5454507/ https://ncbi.nlm.nih.gov/pubmed/28412693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M074278 |
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